WFU

2023年1月13日 星期五

Selected (Peds) Neuroradiology Articles of the Month (Jan 2023)

Selected (Peds) Neuroradiology Articles of the Month (Jan 2023) 


AJNR

1. The Monro-Kelli Doctrine: A Review and Call for Revision
http://www.ajnr.org/content/44/1/2

2. Dilated Optic Nerve Sheath in Mucopolysaccharidosis I: Common and Not Necessarily High Intracranial Pressure
http://www.ajnr.org/content/44/1/91


Radiographics

1. Arterial Spin Labeling: Techniques, Clinical Applications, and Interpretation


NEUROSURGERY

1. Epilepsy Surgery in Young Children With Tuberous Sclerosis Complex: A Novel Hybrid Multimodal Surgical Approach

https://journals.lww.com/neurosurgery/Abstract/2023/02000/Epilepsy_Surgery_in_Young_Children_With_Tuberous.21.aspx


2. Neurosurgical Outcomes for Pediatric Central Nervous System Tumors in the United States

https://journals.lww.com/neurosurgery/Abstract/2023/02000/Neurosurgical_Outcomes_for_Pediatric_Central.22.aspx

Results:

24930 cases from the National Cancer Database pediatric brain tumors from 2004 to 2018. Primary outcomes included 30/90 days postoperative mortality (30M/90M), readmission within 30 days of discharge (30R), and length of inpatient stay (LOS). of all cases were 4753 (19.1%) juvenile pilocytic astrocytomas, 3262 (13.1%) medulloblastomas, 2200 (8.8%) neuronal/mixed neuronal-glial tumors, and 2135 (8.6%) ependymal tumors. Patients aged 0 to 4 years had significantly poorer outcomes than patients in older age groups (90M: 3.5% vs 0.7%-0.9%; 30R: 6.5% vs 3.6%-4.8%; LOS: 12.0 days vs 6.0-8.9 days). Tumor size was a strong predictor of poor outcomes with each additional cm in diameter conferring a 26%, 7%, and 23% increased risk of 90M, 30R, and prolonged LOS, respectively. Data over the study period demonstrated year over year improvements of 4%, 3%, and 2%, respectively, for 90M, 30R, and prolonged LOS. Facilities with a high volume of pediatric tumor cases had improved 90M (1.1% vs 1.5%, P = .041) and LOS (7.6 vs 8.6 days, P < .001). Patients with private health insurance had better outcomes than patients with government insurance.

CONCLUSION: 

There is substantial variability in surgical morbidity and mortality of pediatric CNS tumors. Additional investigation is warranted to reduce outcome differences that may be based on socioeconomic factors.